Causal Role for Neutrophil Elastase in Thoracic Aortic Dissection in Mice.
Yang M, Zhou X, Pearce SWA, Yang Z, Chen Q, Niu K, Liu C, Luo J, Li D, Shao Y, Zhang C, Chen D, Wu Q, Cutillas PR, Zhao L, Xiao Q, Zhang L.
Yang M, et al.
Arterioscler Thromb Vasc Biol. 2023 Oct;43(10):1900-1920. doi: 10.1161/ATVBAHA.123.319281. Epub 2023 Aug 17.
Arterioscler Thromb Vasc Biol. 2023.
PMID: 37589142
Free PMC article.
Finally, adeno-associated virus-2-mediated Tbl1x gene knockdown in aortic smooth muscle cells confirmed a regulatory role for TBL1x in NE-mediated TAD formation. CONCLUSIONS: We unravel a critical role of NE and its target TBL1x in regulating inflammatory cell migration an …
Finally, adeno-associated virus-2-mediated Tbl1x gene knockdown in aortic smooth muscle cells confirmed a regulatory role for TBL1x i …